Benidipine Inhibits Expression of ET-1 and TGF-.BETA.1 in Dahl Salt-Sensitive Hypertensive Rats.
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چکیده
منابع مشابه
Prehypertensive Dahl Salt-Sensitive and Dahl Salt-Resistant Rats
Prehypertensive Dahl salt-sensitive rats on low sodium diet have impaired baroreceptor and cardiopulmonary receptor function as compared with Dahl salt-resistant control rats. We tested whether these abnormalities influenced the ability of conscious prehypertensive Dahl saltsensitive rats to excrete a moderate intravenous isotonic saline volume load (0.9% NaCl, 3% body weight i.v.). During cont...
متن کاملPrehypertensive Dahl Salt-Sensitive Rats
Dahl salt-sensitive rats fed a low salt diet demonstrate functional impairment in baroreflex control of cardiovascular function prior to the development of hypertension. The purpose of this study was to identify the mechanism(s) responsible for impaired baroreflex control in prehypertensive Dahl salt-sensitive rats. To examine the central and efferent portions of the baroreflex arc, we electric...
متن کاملSalt-Induced Hypertension in Dahl Salt-Sensitive Rats
Cardiac output, blood volume, total peripheral resistance, and renal blood flow were measured in awake salt-sensitive and salt-resistant Dahl rats on normal rat chow (1% NaCl) and on high salt (8% NaCl) diets. Rats were studied after 4, 8, and 46 weeks on a 1% NaCl diet and after 4 and 8 weeks on an 8% NaCl diet Salt-sensitive rats on 8% NaCl for 4 weeks developed systolic hypertension; by 8 we...
متن کاملAbnormal baroreflex control of heart rate in prehypertensive and hypertensive Dahl genetically salt-sensitive rats.
This study tested the hypothesis that in the Dahl model of genetic hypertension abnormal baroreflex function may precede and contribute to the development of hypertension. Sensitivity of baroreflex control of heart rate was assessed in conscious sensitive (S) and resistant (R) Dahl rats fed a high or low salt diet. Sensitivity of baroreflex control of heart rate was lower in S rats fed low salt...
متن کاملLongitudinal study of the hindquarter vasculature during development in spontaneously hypertensive and Dahl salt-sensitive rats.
The purpose of this study was to examine vascular structural alterations longitudinally in spontaneous and Dahl genetic hypertension. Hypertensive and control animals were studied at 5,9-11, and 17-19 weeks of age to permit analysis of prehypertensive, early and established hypertensive stages. Minimal and maximal resistance of the hindquarter vasculature was used as a functional assessment of ...
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ژورنال
عنوان ژورنال: Hypertension Research
سال: 2001
ISSN: 0916-9636
DOI: 10.1291/hypres.24.241